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Lab of Metabolomics
Key lab of Drug Metabolism and Pharmacokinetics
China Pharmaceutical University
24 Tongjia Xiang
Phone: +86 25 83271081, 13770606216
PhD Degree of Pharmacology, China Pharmaceutical University, June 2002. Senior researcher in the Key Laboratory of Drug Metabolism and Pharmacokinetics, Director of the Laboratory of Metabolomics, China Pharmaceutical University. Majored in metabolomics, drug Metabolism and pharmacokinetics, mechanism of metabolic diseases and the modulation on metabolic pathways involved in various diseases.
Dr. Aa had ever worked as Postdoc in Umea University, Sweden, and University of London, took part in the key project of “Swedish Research Council, Wallenberg Consortium North”(Sweden) and a project raised by Food Standard Agency, UK. After his return back to work in China Pharmaceutical University, Dr. Aa took part in the projects of the National Basic Research Program of China 973 Program, the National Key Special Project of Science and Technology for Innovation Drugs of China, and charged four projects of National Natural Science Foundation of the People’s Republic of China in 2011, 2014, 2015 and 2017, respectively. Dr. Aa is a project Leader of the National Key Special Project of Science and Technology for Innovation Drugs of China, the development of key techniques for creative and multiple components, 2017.
During the Postdoc study under the supervision of Prof. Stefan Marklund, Thomas Moritz, Johan Trygg in Umea, Sweden, for the first time, Dr. Aa developed a popular method for global analysis of metabolites in plasma based on GC/TOFMS. This article published in Analytical Chemistry has been extensively cited, and the GC/MS platform has been one of the three most popular tools for metabolomic study worldwide. As the corresponding or first author, a total of 40 SCI articles have been published recent years. Dr. Aa is the reviewer for international Journals of metabolomics, Molecular Biosystem, Analyitcal Chemistry, Drug Metabolism and Disposition, Journal of Chromatography B, Acta Pharmacologica Sinica, Journal of Pharmaceutical and Biomedical Analysis, electrophoresis and five Chinese Core Journals and the Editor member of Chinese Journal of clinical pharmacology and therapeutics and Acta Pharmaceutica Sinica. Totally, Dr Aa has been awarded once in 2007 National Science & Technology Progress Award, Second Prize, once in 2012 Frist Prize Award Progress in Science & Technology of the Ministry of Education，twice in 2012 and 2017 Frist Prize Award for Progress in Science & Technology of Jiangsu Province.
1. Drug metabolism enzymes and transporters
2. Drug metabolism and Pharmacokinetics of Creative drugs
3. Metabolomics, metabolic markers and metabolic pathways involved in drug efficacy and toxicity
4. Drug metabolism and Pharmacokinetics of traditional Chinese Medicine